Modelling and Simulation of Thermal Effect of Metastasis of Tumors in Human Limbs

The present paper deals with the thermal effect model of temperature distribution in dermal layers of elliptical shaped human limbs involving two uniformly perfused tumor in dermis layer. Here the tumor is characterized by uncontrolled rates of metabolic heat generation. The normal tissues are characterized by self controlled metabolic heat generation. It is assumed that first there was only one tumor in the dermis but after sometime another tumor has developed at other position in the limb due to metastasis. The structure of the region has been taken into account by dividing the dermal region of the human limb into five layers. The outermost layer is the epidermis. Below the epidermis are the three layers of dermis followed by a layer of subermal tissues. The innermost solid cylinder is the limb core. Hexahedral elements have been used to discretize the whole region. Appropriate boundary conditions have been framed using the physical conditions. The seminumerical method has been used to obtain the temperature profiles.